김지훈 선임연구원

Phone

02-958-5065

E-mail

jihoonkim@kist.re.kr

Office

Homepage

– 서울대학교 생명과학부 박사 (M.S. / Ph.D. 2017)

– 건국대학교 생명과학과 학사 (B.S. 2009)

– 박사 후 연구원, 서울대학교 생명과학부 (2017-2021)

 

– 선임 연구원, 한국과학기술연구원 (2121- Present)

-마우스 유전학 (Mouse genetics)

 

-발생학 (Developmental biology)

 

-분자 생물학 (Molecular biology)

 

-줄기세포 (Stem cell)

 

-노화 (Gerontology)

 

-골격근 (Skeletal muscle)

 

-운동 신경 (Motor Neuron)

 

-유전자 치료기술 (Gene Therapy)

 

-오가노이드 (Organoid)

– 논문

 

  1. Ji-Yun Seo, Jong-Seol Kang, Ye Lynne Kim, Ji-Hoon Kim, Young-Woo Jo, Sang-Hyeon Hann, Jieon Park, Inkuk Park, Hyerim Park, Kyusang Yoo, Joonwoo Rhee, Jung-Wee Park, Yong Chan Ha and Young-Yun Kong. Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis. Nat. Commun., Accepted for publication.
  2. JiHoon Kim, Inkuk Park, Hijai R. Shin, Joonwoo Rhee, Ji‐Yun Seo, Young‐Woo Jo, Kyusang Yoo, Sang‐Hyeon Hann, Jong‐Seol Kang, Jieon Park, Ye Lynne Kim, Ju‐Yeon Moon, Man Ho Choi, Young‐Yun Kong. The hypothalamic–pituitary–gonadal axis controls muscle stem cell senescence through autophagosome clearance. J. Cachexia Sarcopenia Muscle (2021). DOI: 10 .1002/jcsm.12653
  3. Ji-Hoon Kim, Man Ho Choi. Embryonic development and adult regeneration of the adrenal gland. Endocrinol. Metab., 35:765-773 (2020).
  4. Seo JY, Kim JH, Kong YY (2019) Unraveling the paradoxical action of androgens on muscle stem cells. Mol Cells 42(2):97-103 (2019).
  5. Jinwoo Seong, Nam-Shik Kim, Jee-Ah Kim, Wonbin Lee, Ji-Yun Seo, Min Kyu Yum, Ji-Hoon Kim, Inkuk Park, Jong-Seol Kang, Sung-Hwan Bae, Cheol-Heui Yun, Young-Yun Kong. Side branching and luminal lineage commitment by ID2 in developing mammary glands. Development, 145(14):165258 (2018).
  6. Seungtae Moon, Sun-Kyoung Im, Nackhyoung Kim, Hyesook Youn, Ui-Hyun Park, Joo-Yeon Kim, A.-Reum Kim, So-Jung An, Ji-Hoon Kim, Woong Sun, Jin-Taek Hwang, Eun-Joo Kim & Soo-Jong Um. Asxl1 exerts an anti-proliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death & Disease, 9(11):1118 (2018).
  7. Kim JH, Han GC, Seo JY, Park I, Park W, Jeong HW, Lee SH, Bae SH, Seong J, Yum MK, Hann SH, Kwon YG, Seo D, Choi MH, Kong YY (2016) Sex hormones establish a reserve pool of adult muscle stem cells. Nat Cell Biol., 18(9):930-940 (2016).
  8. Minji Seo, Seong-Ok Lee, Ji-Hoon Kim, Yujin Hong, Seongchan Kim, Yeumin Kim, Dal-Hee Min, Young-Yun Kong, Jinwook Shin, Kwangseog Ahn. MAP4-regulated dynein-dependent trafficking of BTN3A1 controls the TBK1–IRF3 signaling axis. PNAS., 113(50):14390-14395 (2016).
  9. Park JH*, Yang SW*, Park JM, Ka SH, Ji-Hoon Kim, YY Kong, Jeon YJ, Seol JH and Chung CH (2016) Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification. Nat. Commun., 7:12513 (2016).
  10. Yum MK, Kang JS, Lee AE, Jo YW, Seo JY, Kim HA, Kim YY, Seong J, Lee EB, Ji-Hoon Kim, Han JM, Kim S, Kong YY. AIMP2 Controls Intestinal Stem Cell Compartments and Tumorigenesis by Modulating Wnt/β-Catenin Signaling. Cancer Res., 76(15):4559-4568 (2016).
  11. Jeong HW, Ji-Hoon Kim, Kim JY, Ha SJ, Kong YY. Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation. PLoS One., 7(4):e36359 (2012).

 

– 특허

 

  1. PHARMACEUTICAL COMPOSITION FOR TREATING SARCOPENIA COMPRISING ACTN3 INHIBITOR (#10-2021-0025830)